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DC Projects => World Community Grid => Topic started by: vaio on August 31, 2005, 01:05:44 PM



Title: Project Status update
Post by: vaio on August 31, 2005, 01:05:44 PM
 Linky (http://www.worldcommunitygrid.org/forums/wcg/viewthread?thread=3757&lastpage=yes#lastpost)


Title: Project Status update
Post by: VAIO GRX616 on August 31, 2005, 02:36:52 PM
Thanks for the heads-up vaio; did anyone click the links in rbonneau's post?  Anyone here understand that stuff?  :eh:


Title: Project Status update
Post by: comp_interrlz on August 31, 2005, 03:38:16 PM
hell no

 :shock:


Title: Project Status update
Post by: fingerle on August 31, 2005, 03:41:19 PM
The most I got was.... (http://home.comcast.net/~fingerlew/S/blasm.gif)


Title: Project Status update
Post by: retsof on August 31, 2005, 09:09:17 PM
Quote from: "VAIO GRX616"
Thanks for the heads-up vaio; did anyone click the links in rbonneau's post?  Anyone here understand that stuff?  :eh:
Rosetta's 81% done...and there's an idea for further refinement with Rosetta phase 2.


Title: Project Status update
Post by: comp_interrlz on September 01, 2005, 04:10:40 AM
Quote from: "retsof"
Quote from: "VAIO GRX616"
Thanks for the heads-up vaio; did anyone click the links in rbonneau's post?  Anyone here understand that stuff?  :eh:
Rosetta's 81% done...and there's an idea for further refinement with Rosetta phase 2.



think we're talkin abot the link that is on the grid post...

all the numbers and letters mean nothing


Title: Project Status update
Post by: retsof on September 02, 2005, 06:17:06 PM
Quote from: "comp_interrlz"
Quote from: "retsof"
Quote from: "VAIO GRX616"
Thanks for the heads-up vaio; did anyone click the links in rbonneau's post?  Anyone here understand that stuff?  :eh:
Rosetta's 81% done...and there's an idea for further refinement with Rosetta phase 2.

think we're talkin abot the link that is on the grid post...
all the numbers and letters mean nothing
I'd have to numbers and letters to explain it, so I'm lost.


Title: Project Status update
Post by: lawrencehardin on September 03, 2005, 10:50:36 PM
Well, the image says that the proteins have been divided up into 104 batches, presumably about the same size.  This is a fuzzy concept, since the Rosetta program takes different amounts of time to fold each protein 10,000 times, to generate the statistics needed to guess at the most probable fold.

78 of the 104 batches have been completely folded and returned to the ISB.  14 are out being folded as of 24 August.  12 batches are still sitting in the server at the ISB, waiting to be downloaded and crunched.  81% completed sounds like a good guess.

For a long time we did not know how many proteins there would be to crunch.  The ISB ran its computers through the Human Genome slowly picking out proteins small enough for Rosetta to handle.  Then, all of a sudden, we started receiving updates talking about a number of proteins from other species important to humans, such as malaria.  Which is just fine by me, since I always regarded that sort of thing as being highly useful.  If a disease uses proteins very similar to ours, then it is not a good drug target.  If it uses some proteins very different from ours, TARGET - blast it.  But the point is - - for a long time the project seemed to have a very indefinite length while they were deciding how many proteins to dump into the hopper and crunch.