The DC Zone

DC Projects => Find-a-Drug => Topic started by: FluffyChicken on August 19, 2005, 12:06:28 PM



Title: Find-a-Drug not Find a Drug
Post by: FluffyChicken on August 19, 2005, 12:06:28 PM
Just thought I'd point out before you get to many people here.



That it is Find-a-Drug not Find a Drug



The hyphens should be in the name



(http://www.find-a-drug.org.uk/images/fad-logo-m.gif)



and here

http://www.find-a-drug.org.uk/aboutus.html



It is always an offically called Find-a-Drug.



EDIT to correct bbcode blah blah....  :lol:


Title: Find-a-Drug not Find a Drug
Post by: vaio on August 19, 2005, 12:12:16 PM
Hi Fluffy  :D



As you have much more knowledge of this project than I...would you like to post an intro to the project?



Just a basic introduction to it......then I could paste it into the info sticky?



No matter if you don't wish to...I can do one myself but you would probably do a much better job.



If you want to do one just write it up in this thread and I will move it to the sticky  :D



Welcome aboard


Title: Find-a-Drug not Find a Drug
Post by: PiNkY on August 19, 2005, 12:41:08 PM
welcome fluffychicken! :D





thanks for the correction, i'll fix the forum title shortly.


Title: Find-a-Drug not Find a Drug
Post by: hob on August 19, 2005, 12:49:32 PM
About Find-a-Drug

Find-a-Drug is a not for profit distributed computing project which was set up by Treweren Consultants, the company who developed the THINK software. Find-a-Drug aims to run a series of projects in parallel addressing a number of diseases which have a major impact on health. We seek to collaborate with the world's leading experts including academics in each therapeutic area. Members may elect to opt in and out of projects at any time using the Find-a-Drug control panel. The progress of each project as well as contributions of our members are published on the web-site. Members can print milestone certificates when they pass milestones for the numbers of molecules processed, the computer time contributed and points generated. The list of members who have found molecules which exhibit the desired biological activity when tested in the laboratory is also published and special active molecule certificates are awarded to these members. It is usual for these certificates to be issued some months after the computer predictions are available and only a subset of the molecules predicted to be active are tested.



Any-one with a PC can help the research by downloading the THINK software. This software runs in background or as a screen-saver so that it does not interfere with normal use of the PC. When the computer is not otherwise being used, the software evaluates the potential of molecules to interact with a protein target. Each molecule that is predicted to interact with the target is considered a "hit" and may become a new drug for treating an important disease. Jobs consisting of about 10,000 molecules are downloaded from the Internet and the list of hits returned. A typical job runs for 6-12 hours on an average PC. The data files downloaded from the Find-a-Drug servers are encrypted as a precaution against a virus or other harmful agent being introduced to the computers.



The initial funding has come from Treweren Consultants but income from partnership agreements to exploit the results will allow Find-a-Drug to become self-funding. Announcements about these agreements and which protein targets they relate to will be made in due course. The results from public interest projects such as the Bioterrorism Antidote project will be made available to approved academic and government research laboratories without charge. We welcome proposals from academics to consider specific protein targets and are sympathetic to requests for a subset of the results. Our preferred partners are small pharmaceutical companies including University spin-off companies with scientific expertise in the therapeutic area who can utilise the results effectively. We are working towards Find-a-Drug.org gaining charitable status which would provide certain tax benefits and independence. The trustees of Find-a-Drug.org will distribute any profits for research. As the costs of running this project are low, research grants would include a substantial part of any income from licensing the results and royalties on sales.



The first internet based computing project which used the THINK virtual screening software was hosted by United Devices in collaboration with the Oxford University. Funding for the original project came from the National Foundation for Cancer Research (NFCR) and Intel Corporation. The science for this project was directed by Keith Davies while he was an honorary research fellow at the University. Keith is a founding Director of Treweren Consultants and Find-a-Drug. The Find-a-Drug cancer project is a reflection on Keith's personal motivations and interest in continuing the work begun with United Devices developing therapies for a disease which affects one in four individuals.



Find-a-Drug has benefited from the experience of the earlier project. In part due to assistance from Intel, the latest version of THINK is approximately 40 times faster than version 1.03 used on the United Devices platform. In addition, Find-a-Drug uses geographically dispersed servers which provides superior redundancy and avoids contention downloading jobs and uploading results. The proprietary network communication software uses the standard protocol (http) with encryption of all data and results files. This provides one of the highest levels of security without compromising server performance as well as facilitating the detection of tampering with files.



Find-a-Drug acknowledges the assistance from volunteers creating this site and the software.



http://www.find-a-drug.biz/frame.html :fridaynite:


Title: Find-a-Drug not Find a Drug
Post by: vaio on August 19, 2005, 01:01:50 PM
Thanks hob......will post it up shortly  :D


Title: Find-a-Drug not Find a Drug
Post by: vaio on September 11, 2005, 06:42:56 PM
If a team has been inactive for a while does it get dumped?
I cannot find the JTS in the team listings


Title: Find-a-Drug not Find a Drug
Post by: phicks on September 11, 2005, 07:13:17 PM
Your team #206 in the rankings.


Title: Find-a-Drug not Find a Drug
Post by: vaio on September 11, 2005, 07:18:12 PM
I found an entry by searching..........couldn't find it cos nobody is in it.

But according to my lil browser there are 200 teams..so being 206th is extra cool  :P


Title: Find-a-Drug not Find a Drug
Post by: phicks on September 11, 2005, 07:21:07 PM
check here on pg. 5 it goes up to #229.  :D

http://fadstats.com/


Title: Find-a-Drug not Find a Drug
Post by: vaio on September 11, 2005, 07:23:17 PM
Grazi.......My memory is off as usual....I thought it was 2209  :P


Title: Find-a-Drug not Find a Drug
Post by: phicks on September 11, 2005, 07:27:16 PM
:think:


Title: Find-a-Drug not Find a Drug
Post by: vaio on September 11, 2005, 07:28:36 PM
the team number......thought it was 2209...........wasn't far off considering i haven't done any for a squillion years


Title: Find-a-Drug not Find a Drug
Post by: vaio on September 11, 2005, 07:30:14 PM
stupid name..........smapperazzi  :roll:


Title: Find-a-Drug not Find a Drug
Post by: vaio on September 11, 2005, 08:02:15 PM
gonna quietly do a lil work....for research purposes and all.


Title: Find-a-Drug not Find a Drug
Post by: vaio on September 11, 2005, 08:48:56 PM
cor.almost forgot what it was like to run cancer work  :P


Title: Find-a-Drug not Find a Drug
Post by: PiNkY on September 11, 2005, 09:02:09 PM
cor that pup says cor a lot :P


Title: Find-a-Drug not Find a Drug
Post by: vaio on September 11, 2005, 09:07:36 PM
does he?

Cor  :hoghappy:

Rather I used choice scouse?  :wink:


Title: Find-a-Drug not Find a Drug
Post by: PiNkY on September 11, 2005, 09:10:04 PM
the noone would understand you :lol:


Title: Find-a-Drug not Find a Drug
Post by: oVo on September 12, 2005, 02:34:12 AM
What is this cor?



While we are at it, what is the A&M connection anyway?


Title: Find-a-Drug not Find a Drug
Post by: PiNkY on September 12, 2005, 02:40:41 AM
gotta ask the spotted one :lol:



hmm, gotta love how we manage to stay around topic around here :P


Title: Find-a-Drug not Find a Drug
Post by: oVo on September 12, 2005, 03:21:39 AM
Quote from: "PiNkY"
gotta ask the spotted one :lol:



I thought I just did.  :eh:


Title: Find-a-Drug not Find a Drug
Post by: PiNkY on September 12, 2005, 03:24:28 AM
:doh:


carry on then :lol:


Title: Find-a-Drug not Find a Drug
Post by: FluffyChicken on September 12, 2005, 03:35:34 AM
ontopic :
anyone watching the cricket ?

offtopic:
spotted dog,  send an email off to [email protected] (or better [email protected]) and Keith will change yor name for you.


Title: Find-a-Drug not Find a Drug
Post by: oVo on September 12, 2005, 03:37:11 AM
No, but there is a cricket watching me!  :shock:



Does that count for anything?  :P


Title: Find-a-Drug not Find a Drug
Post by: vaio on September 12, 2005, 06:53:29 AM
Cricket?

A & M?

My F-a-D config has yet to encounter either of these  :?