Well, the image says that the proteins have been divided up into 104 batches, presumably about the same size. This is a fuzzy concept, since the Rosetta program takes different amounts of time to fold each protein 10,000 times, to generate the statistics needed to guess at the most probable fold.
78 of the 104 batches have been completely folded and returned to the ISB. 14 are out being folded as of 24 August. 12 batches are still sitting in the server at the ISB, waiting to be downloaded and crunched. 81% completed sounds like a good guess.
For a long time we did not know how many proteins there would be to crunch. The ISB ran its computers through the Human Genome slowly picking out proteins small enough for Rosetta to handle. Then, all of a sudden, we started receiving updates talking about a number of proteins from other species important to humans, such as malaria. Which is just fine by me, since I always regarded that sort of thing as being highly useful. If a disease uses proteins very similar to ours, then it is not a good drug target. If it uses some proteins very different from ours, TARGET - blast it. But the point is - - for a long time the project seemed to have a very indefinite length while they were deciding how many proteins to dump into the hopper and crunch.
The DC Zone
